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KMID : 0384320130340040289
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Korean Journal of Family Medicine
2013 Volume.34 No. 4 p.289 ~ p.292
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A Case of Incidentally Discovered Subclinical Cushing Syndrome in a Patient with Chronic Fatigue and Anxiety
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Nam Kyung-Jee
Lee Sang-Yeoup
Cho Young-Hye
Choi Eun-Jung
Jeong Dong-Wook
Kim Yun-Jin
Lee Jeong-Gyu
Lee Yu-Hyeon
Tak Young-Jin
Yi Dong-Won
Park Sung-Woo
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Abstract
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Subclinical Cushing syndrome (SCS) is a hypothalamic-pituitary-adrenal axis abnormality characterized by autonomous cortisol secretion in patients with no typical signs or symptoms of Cushing syndrome. SCS patients may have adverse metabolic and cardiovascular effects due to slight, but continuous glucocorticoid secretion. Glucocorticoids also affect behavior, mood, neural activity, and a number of specific biochemical processes in the central nervous system. Here, we report a case of SCS due to an adrenal incidentaloma in a hypertensive diabetic patient who presented with chronic fatigue and anxiety that disappeared after the removal of the adrenal adenoma.
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KEYWORD
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Subclinical Cushing Syndrome, Adrenal Incidentaloma, Chronic Fatigue, Anxiety
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